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Immunogenicity and Efficacy of Single Antigen Gp63, Polytope and PolytopeHSP70 DNA Vaccines against Visceral Leishmaniasis in Experimental Mouse Model

Polytope approach of genetic immunization is a promising strategy for the prevention of infectious disease as it is capable of generating effective cell mediated immunity by delivering the T cell epitopes assembled in series. Leishmaniasis is a significant world wide health problem for which no vacc...

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Detalles Bibliográficos
Autores principales: Sachdeva, Rakhee, Banerjea, Akhil C., Malla, Nancy, Dubey, Mohan Lal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780826/
https://www.ncbi.nlm.nih.gov/pubmed/19956549
http://dx.doi.org/10.1371/journal.pone.0007880