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Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis In Vivo

OBJECTIVE: Insulin represses the expression of gluconeogenic genes at the mRNA level, but the hormone appears to have only weak inhibitory effects in vivo. The aims of this study were 1) to determine the maximal physiologic effect of insulin, 2) to determine the relative importance of its effects on...

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Detalles Bibliográficos
Autores principales: Edgerton, Dale S., Ramnanan, Christopher J., Grueter, Carrie A., Johnson, Kathryn M.S., Lautz, Margaret, Neal, Doss W., Williams, Phillip E., Cherrington, Alan D.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780867/
https://www.ncbi.nlm.nih.gov/pubmed/19755527
http://dx.doi.org/10.2337/db09-0328