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Differences in the Central Anorectic Effects of Glucagon-Like Peptide-1 and Exendin-4 in Rats

OBJECTIVE: Glucagon-like peptide (GLP)-1 is a regulatory peptide synthesized in the gut and the brain that plays an important role in the regulation of food intake. Both GLP-1 and exendin (Ex)-4, a long-acting GLP-1 receptor (GLP-1r) agonist, reduce food intake when administered intracerebroventricu...

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Detalles Bibliográficos
Autores principales: Barrera, Jason G., D'Alessio, David A., Drucker, Daniel J., Woods, Stephen C., Seeley, Randy J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780868/
https://www.ncbi.nlm.nih.gov/pubmed/19741167
http://dx.doi.org/10.2337/db09-0281