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Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

OBJECTIVE: Recent studies in humans and animal models of obesity have shown increased adipose tissue activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which amplifies local tissue glucocorticoid concentrations. The reasons for this 11β-HSD1 dysregulation are unknown. Here, we tested wh...

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Detalles Bibliográficos
Autores principales: Nyirenda, Moffat J., Carter, Roderick, Tang, Justin I., de Vries, Annick, Schlumbohm, Christina, Hillier, Stephen G., Streit, Frank, Oellerich, Michael, Armstrong, Victor W., Fuchs, Eberhard, Seckl, Jonathan R.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780883/
https://www.ncbi.nlm.nih.gov/pubmed/19720800
http://dx.doi.org/10.2337/db09-0873