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Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1
OBJECTIVE: Recent studies in humans and animal models of obesity have shown increased adipose tissue activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which amplifies local tissue glucocorticoid concentrations. The reasons for this 11β-HSD1 dysregulation are unknown. Here, we tested wh...
Autores principales: | Nyirenda, Moffat J., Carter, Roderick, Tang, Justin I., de Vries, Annick, Schlumbohm, Christina, Hillier, Stephen G., Streit, Frank, Oellerich, Michael, Armstrong, Victor W., Fuchs, Eberhard, Seckl, Jonathan R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780883/ https://www.ncbi.nlm.nih.gov/pubmed/19720800 http://dx.doi.org/10.2337/db09-0873 |
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