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Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77

OBJECTIVE: Nur77 is an orphan nuclear receptor with pleotropic functions. Previous studies have identified Nur77 as a transcriptional regulator of glucose utilization genes in skeletal muscle and gluconeogenesis in liver. However, the net functional impact of these pathways is unknown. To examine th...

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Detalles Bibliográficos
Autores principales: Chao, Lily C., Wroblewski, Kevin, Zhang, Zidong, Pei, Liming, Vergnes, Laurent, Ilkayeva, Olga R., Ding, Shi Ying, Reue, Karen, Watt, Matthew J., Newgard, Christopher B., Pilch, Paul F., Hevener, Andrea L., Tontonoz, Peter
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780886/
https://www.ncbi.nlm.nih.gov/pubmed/19741162
http://dx.doi.org/10.2337/db09-0763