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Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77
OBJECTIVE: Nur77 is an orphan nuclear receptor with pleotropic functions. Previous studies have identified Nur77 as a transcriptional regulator of glucose utilization genes in skeletal muscle and gluconeogenesis in liver. However, the net functional impact of these pathways is unknown. To examine th...
Autores principales: | Chao, Lily C., Wroblewski, Kevin, Zhang, Zidong, Pei, Liming, Vergnes, Laurent, Ilkayeva, Olga R., Ding, Shi Ying, Reue, Karen, Watt, Matthew J., Newgard, Christopher B., Pilch, Paul F., Hevener, Andrea L., Tontonoz, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780886/ https://www.ncbi.nlm.nih.gov/pubmed/19741162 http://dx.doi.org/10.2337/db09-0763 |
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