Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

OBJECTIVE: Alteration in endoplasmic reticulum (ER) stress in diabetic hearts and its effect on cytoprotective signaling are unclear. Here, we examine the hypothesis that ER stress in diabetic hearts impairs phospho–glycogen synthase kinase (GSK)-3β–mediated suppression of mitochondrial permeability...

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Detalles Bibliográficos
Autores principales: Miki, Takayuki, Miura, Tetsuji, Hotta, Hiroyuki, Tanno, Masaya, Yano, Toshiyuki, Sato, Takahiro, Terashima, Yoshiaki, Takada, Akifumi, Ishikawa, Satoko, Shimamoto, Kazuaki
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780889/
https://www.ncbi.nlm.nih.gov/pubmed/19755525
http://dx.doi.org/10.2337/db09-0158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780889/
https://www.ncbi.nlm.nih.gov/pubmed/19755525
http://dx.doi.org/10.2337/db09-0158

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