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B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity

BACKGROUND: The etiology of the neurogenerative disease multiple sclerosis (MS) is unknown. The leading hypotheses suggest that MS is the result of exposure of genetically susceptible individuals to certain environmental factor(s). Herpesviruses and human endogenous retroviruses (HERVs) represent po...

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Detalles Bibliográficos
Autores principales: Brudek, Tomasz, Christensen, Tove, Aagaard, Lars, Petersen, Thor, Hansen, Hans J, Møller-Larsen, Anné
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780989/
https://www.ncbi.nlm.nih.gov/pubmed/19917105
http://dx.doi.org/10.1186/1742-4690-6-104