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B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity
BACKGROUND: The etiology of the neurogenerative disease multiple sclerosis (MS) is unknown. The leading hypotheses suggest that MS is the result of exposure of genetically susceptible individuals to certain environmental factor(s). Herpesviruses and human endogenous retroviruses (HERVs) represent po...
Autores principales: | Brudek, Tomasz, Christensen, Tove, Aagaard, Lars, Petersen, Thor, Hansen, Hans J, Møller-Larsen, Anné |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780989/ https://www.ncbi.nlm.nih.gov/pubmed/19917105 http://dx.doi.org/10.1186/1742-4690-6-104 |
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