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A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427

BACKGROUND: Human African Trypanosomiasis (HAT) is caused by two trypanosome species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Current drugs available for the treatment of HAT have significant issues related to toxicity, administration regimes with limited effectiveness acros...

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Detalles Bibliográficos
Autores principales: Sykes, Melissa L, Avery, Vicky M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781010/
https://www.ncbi.nlm.nih.gov/pubmed/19909542
http://dx.doi.org/10.1186/1756-3305-2-54