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Reverse genetics through random mutagenesis in Histoplasma capsulatum
BACKGROUND: The dimorphic fungal pathogen Histoplasma capsulatum causes respiratory and systemic disease in humans and other mammals. Progress in understanding the mechanisms underlying the biology and the pathogenesis of Histoplasma has been hindered by a shortage of methodologies for mutating a ge...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781022/ https://www.ncbi.nlm.nih.gov/pubmed/19919692 http://dx.doi.org/10.1186/1471-2180-9-236 |