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Med8, Med18, and Med20 subunits of the Mediator head domain are interdependent upon each other for folding and complex formation

We have studied folding and complex formation of the yeast Mediator head-module protein subunits Med8, Med18, and Med20. Using a combination of immunoprecipitation, far-UV circular dichroism, and fluorescence measurements on recombinantly expressed and denatured proteins that were allowed to renatur...

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Detalles Bibliográficos
Autores principales: Adler, David, Rahaman, Hamidur, Wittung-Stafshede, Pernilla, Björklund, Stefan
Formato: Texto
Lenguaje:English
Publicado: National Academy of Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781058/
https://www.ncbi.nlm.nih.gov/pubmed/19934057
http://dx.doi.org/10.1073/pnas.0907645106