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Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC

BACKGROUND: Cancer/testis antigens (CTAs) were first discovered as immunogenic targets normally expressed in germline cells, but differentially expressed in a variety of human cancers. In this study, we used an integrative epigenetic screening approach to identify coordinately expressed genes in hum...

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Detalles Bibliográficos
Autores principales: Glazer, Chad A., Smith, Ian M., Ochs, Michael F., Begum, Shahnaz, Westra, William, Chang, Steven S., Sun, Wenyue, Bhan, Sheetal, Khan, Zubair, Ahrendt, Steven, Califano, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781168/
https://www.ncbi.nlm.nih.gov/pubmed/19997593
http://dx.doi.org/10.1371/journal.pone.0008189