Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism

The aim of the present study was to test the hypothesis that elevation of prorenin in plasma is sufficient to induce cardiac fibrosis. Normotensive cyp1a1ren-2 transgenic rats with normal plasma prorenin and aldosterone levels were given 0.125% indole-3-carbinol (I3C) orally for a period of 12 wk. P...

Descripción completa

Detalles Bibliográficos
Autores principales: Peters, Jörg, Schlüter, Torsten, Riegel, Thomas, Peters, Barbara S., Beineke, Andreas, Maschke, Ulrike, Hosten, Norbert, Mullins, John J., Rettig, Rainer
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781377/
https://www.ncbi.nlm.nih.gov/pubmed/19749160
http://dx.doi.org/10.1152/ajpheart.01135.2008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781377/
https://www.ncbi.nlm.nih.gov/pubmed/19749160
http://dx.doi.org/10.1152/ajpheart.01135.2008

Ejemplares similares