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Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro

We have examined function of the bacterial β replication clamp in the different steps of methyl-directed DNA mismatch repair. The mismatch-, MutS-, and MutL-dependent activation of MutH is unaffected by the presence or orientation of loaded β clamp on either 3′ or 5′ heteroduplexes. Similarly, β is...

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Detalles Bibliográficos
Autores principales: Pluciennik, Anna, Burdett, Vickers, Lukianova, Olga, O'Donnell, Mike, Modrich, Paul
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781695/
https://www.ncbi.nlm.nih.gov/pubmed/19783657
http://dx.doi.org/10.1074/jbc.M109.054528