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A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis

Motivation: Deregulated signaling cascades are known to play a crucial role in many pathogenic processes, among them are tumor initiation and progression. In the recent past, modern experimental techniques that allow for measuring the amount of mRNA transcripts of almost all known human genes in a t...

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Detalles Bibliográficos
Autores principales: Keller, Andreas, Backes, Christina, Gerasch, Andreas, Kaufmann, Michael, Kohlbacher, Oliver, Meese, Eckart, Lenhof, Hans-Peter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781748/
https://www.ncbi.nlm.nih.gov/pubmed/19713416
http://dx.doi.org/10.1093/bioinformatics/btp510