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Increasing the coverage of a metapopulation consensus genome by iterative read mapping and assembly
Motivation: Most microbial species can not be cultured in the laboratory. Metagenomic sequencing may still yield a complete genome if the sequenced community is enriched and the sequencing coverage is high. However, the complexity in a natural population may cause the enrichment culture to contain m...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781756/ https://www.ncbi.nlm.nih.gov/pubmed/19542148 http://dx.doi.org/10.1093/bioinformatics/btp377 |