Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions

BACKGROUND: Hypoxia inducible factor-1 alpha (HIF-1α) protein is rapidly degraded under normoxic conditions. When oxygen tensions fall HIF-1α protein stabilizes and transactivates genes involved in adaptation to hypoxic conditions. We have examined the normoxic expression of HIF-1α RNA and protein i...

Descripción completa

Detalles Bibliográficos
Autores principales: Mills, Caroline N, Joshi, Sandeep S, Niles, Richard M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781803/
https://www.ncbi.nlm.nih.gov/pubmed/19919690
http://dx.doi.org/10.1186/1476-4598-8-104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781803/
https://www.ncbi.nlm.nih.gov/pubmed/19919690
http://dx.doi.org/10.1186/1476-4598-8-104

Ejemplares similares