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Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions
BACKGROUND: Hypoxia inducible factor-1 alpha (HIF-1α) protein is rapidly degraded under normoxic conditions. When oxygen tensions fall HIF-1α protein stabilizes and transactivates genes involved in adaptation to hypoxic conditions. We have examined the normoxic expression of HIF-1α RNA and protein i...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781803/ https://www.ncbi.nlm.nih.gov/pubmed/19919690 http://dx.doi.org/10.1186/1476-4598-8-104 |