Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities

BACKGROUND: PEA-15 is a phosphoprotein that binds and regulates ERK MAP kinase and RSK2 and is highly expressed throughout the brain. PEA-15 alters c-Fos and CREB-mediated transcription as a result of these interactions. To determine if PEA-15 contributes to the function of the nervous system we tes...

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Detalles Bibliográficos
Autores principales: Ramos, Joe W, Townsend, David A, Piarulli, Dawn, Kolata, Stefan, Light, Kenneth, Hale, Gregory, Matzel, Louis D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781817/
https://www.ncbi.nlm.nih.gov/pubmed/19917132
http://dx.doi.org/10.1186/1471-2202-10-134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781817/
https://www.ncbi.nlm.nih.gov/pubmed/19917132
http://dx.doi.org/10.1186/1471-2202-10-134

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