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Signaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation

Apoptosis rather than differentiation is a physiological process during myogenesis and muscle regeneration. When cultured myoblasts were induced to differentiate, we detected an increase in caspase 8 activity. Pharmacological inhibition of caspase 8 activity decreased apoptosis. Expression of a domi...

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Detalles Bibliográficos
Autores principales: O’Flaherty, J., Mei, Y., Freer, M., Weyman, C. M.
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782111/
https://www.ncbi.nlm.nih.gov/pubmed/17041756
http://dx.doi.org/10.1007/s10495-006-0196-4