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Signaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation
Apoptosis rather than differentiation is a physiological process during myogenesis and muscle regeneration. When cultured myoblasts were induced to differentiate, we detected an increase in caspase 8 activity. Pharmacological inhibition of caspase 8 activity decreased apoptosis. Expression of a domi...
Autores principales: | O’Flaherty, J., Mei, Y., Freer, M., Weyman, C. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782111/ https://www.ncbi.nlm.nih.gov/pubmed/17041756 http://dx.doi.org/10.1007/s10495-006-0196-4 |
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