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Interaction of HP1 and Brg1/Brm with the Globular Domain of Histone H3 Is Required for HP1-Mediated Repression

The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain. The chromo-domain binds histone H3 tails methylated on lysine 9. However, in vivo and in vitro experiments have...

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Detalles Bibliográficos
Autores principales: Lavigne, Marc, Eskeland, Ragnhild, Azebi, Saliha, Saint-André, Violaine, Jang, Suk Min, Batsché, Eric, Fan, Hua-Ying, Kingston, Robert E., Imhof, Axel, Muchardt, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782133/
https://www.ncbi.nlm.nih.gov/pubmed/20011120
http://dx.doi.org/10.1371/journal.pgen.1000769