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Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication

Background information. Centrosome duplication normally parallels with DNA replication and is responsible for correct segregation of replicated DNA into the daughter cells. Although geminin interacts with Cdt1 to prevent loading of MCMs (minichromosome maintenance proteins) on to the replication ori...

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Detalles Bibliográficos
Autores principales: Lu, Fei, Lan, Rongfeng, Zhang, Hongyin, Jiang, Qing, Zhang, Chuanmao
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782310/
https://www.ncbi.nlm.nih.gov/pubmed/18798731
http://dx.doi.org/10.1042/BC20080109