Overexpression of the malate–aspartate NADH shuttle member Aralar1 in the clonal β-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism

In the present study, we have investigated the effects of the transduction with recombinant adenovirus AdCA-Aralar1 (aspartate–glutamate carrier 1) on the metabolism, function and secretory properties of the glucose- and amino-acid-responsive clonal insulin-secreting cell line BRIN-BD11. Aralar1 ove...

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Detalles Bibliográficos
Autores principales: Bender, Katrin, Maechler, Pierre, McClenaghan, Neville H., Flatt, Peter R., Newsholme, Philip
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782311/
https://www.ncbi.nlm.nih.gov/pubmed/19344310
http://dx.doi.org/10.1042/CS20090126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782311/
https://www.ncbi.nlm.nih.gov/pubmed/19344310
http://dx.doi.org/10.1042/CS20090126

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