Reduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibition

Alterations within the RAS (renin–angiotensin system) are pivotal for the development of renal disease. ACE2 (angiotensin-converting enzyme 2) is expressed in the kidney and converts the vasoconstrictor AngII (angiotensin II) into Ang-(1–7), a peptide with vasodilatory and anti-fibrotic actions. Alt...

Descripción completa

Detalles Bibliográficos
Autores principales: Velkoska, Elena, Dean, Rachael G., Burchill, Luke, Levidiotis, Vicki, Burrell, Louise M.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782317/
https://www.ncbi.nlm.nih.gov/pubmed/19698082
http://dx.doi.org/10.1042/CS20090318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782317/
https://www.ncbi.nlm.nih.gov/pubmed/19698082
http://dx.doi.org/10.1042/CS20090318

Ejemplares similares