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Reduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibition
Alterations within the RAS (renin–angiotensin system) are pivotal for the development of renal disease. ACE2 (angiotensin-converting enzyme 2) is expressed in the kidney and converts the vasoconstrictor AngII (angiotensin II) into Ang-(1–7), a peptide with vasodilatory and anti-fibrotic actions. Alt...
Autores principales: | Velkoska, Elena, Dean, Rachael G., Burchill, Luke, Levidiotis, Vicki, Burrell, Louise M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782317/ https://www.ncbi.nlm.nih.gov/pubmed/19698082 http://dx.doi.org/10.1042/CS20090318 |
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