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High Throughput Techniques for Discovering New Glycine Receptor Modulators and their Binding Sites

The inhibitory glycine receptor (GlyR) is a member of the Cys-loop receptor family that mediates inhibitory neurotransmission in the central nervous system. These receptors are emerging as potential drug targets for inflammatory pain, immunomodulation, spasticity and epilepsy. Antagonists that speci...

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Detalles Bibliográficos
Autores principales: Gilbert, Daniel F., Islam, Robiul, Lynagh, Timothy, Lynch, Joseph W., Webb, Timothy I.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782790/
https://www.ncbi.nlm.nih.gov/pubmed/19949449
http://dx.doi.org/10.3389/neuro.02.017.2009