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High Throughput Techniques for Discovering New Glycine Receptor Modulators and their Binding Sites
The inhibitory glycine receptor (GlyR) is a member of the Cys-loop receptor family that mediates inhibitory neurotransmission in the central nervous system. These receptors are emerging as potential drug targets for inflammatory pain, immunomodulation, spasticity and epilepsy. Antagonists that speci...
Autores principales: | Gilbert, Daniel F., Islam, Robiul, Lynagh, Timothy, Lynch, Joseph W., Webb, Timothy I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782790/ https://www.ncbi.nlm.nih.gov/pubmed/19949449 http://dx.doi.org/10.3389/neuro.02.017.2009 |
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