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Automated Design of Synthetic Ribosome Binding Sites to Precisely Control Protein Expression
Microbial engineering often requires fine control over protein expression; for example, to connect genetic circuits 1-7 or control flux through a metabolic pathway 8-13. We have developed a predictive design method for synthetic ribosome binding sites that enables the rational control of a protein...
Autores principales: | Salis, Howard M., Mirsky, Ethan A., Voigt, Christopher A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782888/ https://www.ncbi.nlm.nih.gov/pubmed/19801975 http://dx.doi.org/10.1038/nbt.1568 |
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