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Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses
Muscle stem (satellite) cells are relatively resistant to cell-autonomous aging. Instead, their endogenous signaling profile and regenerative capacity is strongly influenced by the aged P-Smad3, differentiated niche, and by the aged circulation. With respect to muscle fibers, we previously establish...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783265/ https://www.ncbi.nlm.nih.gov/pubmed/19732043 http://dx.doi.org/10.1111/j.1474-9726.2009.00517.x |