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Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses

Muscle stem (satellite) cells are relatively resistant to cell-autonomous aging. Instead, their endogenous signaling profile and regenerative capacity is strongly influenced by the aged P-Smad3, differentiated niche, and by the aged circulation. With respect to muscle fibers, we previously establish...

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Detalles Bibliográficos
Autores principales: Carlson, Morgan E, Conboy, Michael J, Hsu, Michael, Barchas, Laurel, Jeong, Jaemin, Agrawal, Anshu, Mikels, Amanda J, Agrawal, Smita, Schaffer, David V, Conboy, Irina M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783265/
https://www.ncbi.nlm.nih.gov/pubmed/19732043
http://dx.doi.org/10.1111/j.1474-9726.2009.00517.x