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Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies

Bone mineral density (BMD) is a heritable complex trait used in the clinical diagnosis of osteoporosis and the assessment of fracture risk. We performed meta-analysis of five genome-wide association studies of femoral neck and lumbar spine BMD in 19,195 subjects of Northern European descent. We iden...

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Detalles Bibliográficos
Autores principales: Rivadeneira, Fernando, Styrkársdottir, Unnur, Estrada, Karol, Halldórsson, Bjarni V., Hsu, Yi-Hsiang, Richards, J. Brent, Zillikens, M. Carola, Kavvoura, Fotini K., Amin, Najaf, Aulchenko, Yurii S., Cupples, L. Adrienne, Deloukas, Panagiotis, Demissie, Serkalem, Grundberg, Elin, Hofman, Albert, Kong, Augustine, Karasik, David, van Meurs, Joyce B., Oostra, Ben, Pastinen, Tomi, Pols, Huibert A.P., Sigurdsson, Gunnar, Soranzo, Nicole, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Williams, Frances MK, Wilson, Scott G., Zhou, Yanhua, Ralston, Stuart H., van Duijn, Cornelia M., Spector, Timothy, Kiel, Douglas P., Stefansson, Kari, Ioannidis, John P.A., Uitterlinden, André G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783489/
https://www.ncbi.nlm.nih.gov/pubmed/19801982
http://dx.doi.org/10.1038/ng.446