Cargando…
Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies
Bone mineral density (BMD) is a heritable complex trait used in the clinical diagnosis of osteoporosis and the assessment of fracture risk. We performed meta-analysis of five genome-wide association studies of femoral neck and lumbar spine BMD in 19,195 subjects of Northern European descent. We iden...
Autores principales: | Rivadeneira, Fernando, Styrkársdottir, Unnur, Estrada, Karol, Halldórsson, Bjarni V., Hsu, Yi-Hsiang, Richards, J. Brent, Zillikens, M. Carola, Kavvoura, Fotini K., Amin, Najaf, Aulchenko, Yurii S., Cupples, L. Adrienne, Deloukas, Panagiotis, Demissie, Serkalem, Grundberg, Elin, Hofman, Albert, Kong, Augustine, Karasik, David, van Meurs, Joyce B., Oostra, Ben, Pastinen, Tomi, Pols, Huibert A.P., Sigurdsson, Gunnar, Soranzo, Nicole, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Williams, Frances MK, Wilson, Scott G., Zhou, Yanhua, Ralston, Stuart H., van Duijn, Cornelia M., Spector, Timothy, Kiel, Douglas P., Stefansson, Kari, Ioannidis, John P.A., Uitterlinden, André G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783489/ https://www.ncbi.nlm.nih.gov/pubmed/19801982 http://dx.doi.org/10.1038/ng.446 |
Ejemplares similares
-
The rate of meiotic gene conversion varies by sex and age
por: Halldorsson, Bjarni V., et al.
Publicado: (2016) -
Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density
por: Ivarsdottir, Erna V., et al.
Publicado: (2019) -
Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes
por: Glastonbury, Craig A., et al.
Publicado: (2016) -
An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits
por: Hsu, Yi-Hsiang, et al.
Publicado: (2010) -
Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank
por: Olafsdottir, Thorhildur, et al.
Publicado: (2020)