The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell-intrinsic timer of myelination

The bHLH transcription factor Olig1 promotes oligodendrocyte maturation and is required for myelin repair. In this report, we characterize an Olig1-regulated G-protein coupled receptor GPR17 whose function is to oppose the action of Olig1. GPR17 is restricted to oligodendrocyte lineage cells but dow...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Wu, Heng, Wang, Shuzong, Koito, Hisami, Li, Jianrong, Ye, Feng, Hoang, Jenny, Escobar, Sabine S., Gow, Alex, Arnett, Heather A., Trapp, Bruce D., Karandikar, Nitin J., Hsieh, Jenny, Lu, Q. Richard
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783566/
https://www.ncbi.nlm.nih.gov/pubmed/19838178
http://dx.doi.org/10.1038/nn.2410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783566/
https://www.ncbi.nlm.nih.gov/pubmed/19838178
http://dx.doi.org/10.1038/nn.2410

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