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The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell-intrinsic timer of myelination
The bHLH transcription factor Olig1 promotes oligodendrocyte maturation and is required for myelin repair. In this report, we characterize an Olig1-regulated G-protein coupled receptor GPR17 whose function is to oppose the action of Olig1. GPR17 is restricted to oligodendrocyte lineage cells but dow...
Autores principales: | Chen, Ying, Wu, Heng, Wang, Shuzong, Koito, Hisami, Li, Jianrong, Ye, Feng, Hoang, Jenny, Escobar, Sabine S., Gow, Alex, Arnett, Heather A., Trapp, Bruce D., Karandikar, Nitin J., Hsieh, Jenny, Lu, Q. Richard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783566/ https://www.ncbi.nlm.nih.gov/pubmed/19838178 http://dx.doi.org/10.1038/nn.2410 |
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