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Rates of in situ transcription and splicing in large human genes

Transcription and splicing must proceed over genomic distances of hundreds of kilobases in many human genes. However, the rates and mechanisms of these processes are poorly understood. We have used the compound 5,6-Dichlorobenzimidazole 1-b-D-ribofuranoside (DRB) that reversibly blocks gene transcri...

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Detalles Bibliográficos
Autores principales: Singh, Jarnail, Padgett, Richard A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783620/
https://www.ncbi.nlm.nih.gov/pubmed/19820712
http://dx.doi.org/10.1038/nsmb.1666