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Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

Aberrant neuronal re-entry into the cell cycle is emerging as a potential pathological mechanism in Alzheimer disease (AD). However, while cyclins, cyclin dependent kinases (CDKs), and other mitotic factors are ectopically expressed in neurons, many of these proteins are also involved in other patho...

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Detalles Bibliográficos
Autores principales: Bonda, David J., Evans, Teresa A., Santocanale, Corrado, Llosá, Jesús Catalá, Viňa, Jose, Bajic, Vladan P., Castellani, Rudy J., Siedlak, Sandra L., Perry, George, Smith, Mark A., Lee, Hyoung-gon
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783633/
https://www.ncbi.nlm.nih.gov/pubmed/19946466