Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells; a crosstalk interrupted by vitamin D(3)

Tumor associated macrophages mediate the link between inflammation and cancer progression. Here we showed that macrophage-derived soluble factors induce canonical Wnt signaling in colon cancer cells and promote their growth. Tumor cells induced the release of IL-1β from macrophages, which induced ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaler, Pawan, Augenlicht, Leonard, Klampfer, Lidija
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783659/
https://www.ncbi.nlm.nih.gov/pubmed/19701245
http://dx.doi.org/10.1038/onc.2009.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783659/
https://www.ncbi.nlm.nih.gov/pubmed/19701245
http://dx.doi.org/10.1038/onc.2009.247

Ejemplares similares