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PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance
Macrophages rapidly engulf apoptotic cells to limit the release of noxious cellular contents and to restrict autoimmune responses against self antigens. Although factors participating in recognition and engulfment of apoptotic cells have been identified, the transcriptional basis for the sensing and...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783696/ https://www.ncbi.nlm.nih.gov/pubmed/19838202 http://dx.doi.org/10.1038/nm.2048 |