PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

Macrophages rapidly engulf apoptotic cells to limit the release of noxious cellular contents and to restrict autoimmune responses against self antigens. Although factors participating in recognition and engulfment of apoptotic cells have been identified, the transcriptional basis for the sensing and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukundan, Lata, Odegaard, Justin I., Morel, Christine R., Heredia, Jose E., Mwangi, Julia W., Ricardo-Gonzalez, Roberto R., Goh, Y.P. Sharon, Eagle, Alex Red, Dunn, Shannon E., Awakuni, Jennifer U.H., Nguyen, Khoa D., Steinman, Lawrence, Michie, Sara A., Chawla, Ajay
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783696/
https://www.ncbi.nlm.nih.gov/pubmed/19838202
http://dx.doi.org/10.1038/nm.2048

Ejemplares similares

Ejemplares similares