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Induction of protective cytotoxic T cell responses by a B cell-based cellular vaccine requires stable expression of antigen

B cell-based cellular vaccines represent a promising approach to active immunotherapy of cancer complementing the use of dendritic cells, especially in pediatric patients and patients with low bone marrow reserves. B cells can be easily prepared in large numbers and readily home to secondary lymphoi...

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Detalles Bibliográficos
Autores principales: Guo, Siqi, Xu, Jun, Denning, Warren, Hel, Zdenek
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783822/
https://www.ncbi.nlm.nih.gov/pubmed/19641529
http://dx.doi.org/10.1038/gt.2009.93