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Induction of protective cytotoxic T cell responses by a B cell-based cellular vaccine requires stable expression of antigen
B cell-based cellular vaccines represent a promising approach to active immunotherapy of cancer complementing the use of dendritic cells, especially in pediatric patients and patients with low bone marrow reserves. B cells can be easily prepared in large numbers and readily home to secondary lymphoi...
Autores principales: | Guo, Siqi, Xu, Jun, Denning, Warren, Hel, Zdenek |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783822/ https://www.ncbi.nlm.nih.gov/pubmed/19641529 http://dx.doi.org/10.1038/gt.2009.93 |
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