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Structural basis of receptor sharing by interleukin 17 cytokines
T helper type 17 (T(H)-17) cells, together with their effector cytokines including interleukin 17 (IL-17) family members, are emerging as key mediators of chronic inflammatory and autoimmune disorders. Here we present the crystal structure of a 1:2 complex of IL-17RA bound to IL-17F. The manner of c...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783927/ https://www.ncbi.nlm.nih.gov/pubmed/19838198 http://dx.doi.org/10.1038/ni.1813 |