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Structural basis of receptor sharing by interleukin 17 cytokines

T helper type 17 (T(H)-17) cells, together with their effector cytokines including interleukin 17 (IL-17) family members, are emerging as key mediators of chronic inflammatory and autoimmune disorders. Here we present the crystal structure of a 1:2 complex of IL-17RA bound to IL-17F. The manner of c...

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Detalles Bibliográficos
Autores principales:	Ely, Lauren K., Fischer, Suzanne, Garcia, K. Christopher
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783927/ https://www.ncbi.nlm.nih.gov/pubmed/19838198 http://dx.doi.org/10.1038/ni.1813

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