Whole-genome resequencing of Escherichia coli K-12 MG1655 undergoing short-term laboratory evolution in lactate minimal media reveals flexible selection of adaptive mutations

BACKGROUND: Short-term laboratory evolution of bacteria followed by genomic sequencing provides insight into the mechanism of adaptive evolution, such as the number of mutations needed for adaptation, genotype-phenotype relationships, and the reproducibility of adaptive outcomes. RESULTS: In the pre...

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Detalles Bibliográficos
Autores principales: Conrad, Tom M, Joyce, Andrew R, Applebee, M Kenyon, Barrett, Christian L, Xie, Bin, Gao, Yuan, Palsson, Bernhard Ø
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784333/
https://www.ncbi.nlm.nih.gov/pubmed/19849850
http://dx.doi.org/10.1186/gb-2009-10-10-r118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784333/
https://www.ncbi.nlm.nih.gov/pubmed/19849850
http://dx.doi.org/10.1186/gb-2009-10-10-r118

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