An optimization framework for unsupervised identification of rare copy number variation from SNP array data

Copy number variants (CNVs) have roles in human disease, and DNA microarrays are important tools for identifying them. In this paper, we frame CNV identification as an objective function optimization problem. We apply our method to data from hundreds of samples, and demonstrate its ability to detect...

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Detalles Bibliográficos
Autores principales: Yavaş, Gökhan, Koyutürk, Mehmet, Özsoyoğlu, Meral, Gould, Meetha P, LaFramboise, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784334/
https://www.ncbi.nlm.nih.gov/pubmed/19849861
http://dx.doi.org/10.1186/gb-2009-10-10-r119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784334/
https://www.ncbi.nlm.nih.gov/pubmed/19849861
http://dx.doi.org/10.1186/gb-2009-10-10-r119

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