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Biologic variability of human foreskin fibroblasts in 2D and 3D culture: implications for a wound healing model

BACKGROUND: The fibroblast-populated 3D collagen matrix is a model of tissue and healing which has been used since the 1980's. It was hypothesized that anchorage disruption of the collagen matrix would produce p53-dependent apoptosis in the embedded fibroblasts, but results of hypothesis testin...

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Detalles Bibliográficos
Autores principales: Carlson, Mark A, Prall, Amy K, Gums, Jeremiah J, Lesiak, Alex, Shostrom, Valerie K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784473/
https://www.ncbi.nlm.nih.gov/pubmed/19922655
http://dx.doi.org/10.1186/1756-0500-2-229