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Biologic variability of human foreskin fibroblasts in 2D and 3D culture: implications for a wound healing model
BACKGROUND: The fibroblast-populated 3D collagen matrix is a model of tissue and healing which has been used since the 1980's. It was hypothesized that anchorage disruption of the collagen matrix would produce p53-dependent apoptosis in the embedded fibroblasts, but results of hypothesis testin...
Autores principales: | Carlson, Mark A, Prall, Amy K, Gums, Jeremiah J, Lesiak, Alex, Shostrom, Valerie K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784473/ https://www.ncbi.nlm.nih.gov/pubmed/19922655 http://dx.doi.org/10.1186/1756-0500-2-229 |
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