Cargando…

Oral high dose ascorbic acid treatment for one year in young CMT1A patients: a randomised, double-blind, placebo-controlled phase II trial

BACKGROUND: High dose oral ascorbic acid substantially improved myelination and locomotor function in a Charcot-Marie-Tooth type 1A mouse model. A phase II study was warranted to investigate whether high dose ascorbic acid also has such a substantial effect on myelination in Charcot-Marie-Tooth type...

Descripción completa

Detalles Bibliográficos
Autores principales: Verhamme, Camiel, de Haan, Rob J, Vermeulen, Marinus, Baas, Frank, de Visser, Marianne, van Schaik, Ivo N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784478/
https://www.ncbi.nlm.nih.gov/pubmed/19909499
http://dx.doi.org/10.1186/1741-7015-7-70